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Medicine that inhibit CYP2D6 exercise, which include paroxetine and quinidine, may trigger reduced clearance of oxycodone which could lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by thirteen%, and t½ elim.Just like all opioid preparations, oxycodone items